How autoimmune diseases start, why your immune system attacks your own body, and what the clinical evidence says about reversing them through diet.
Antiphospholipid syndrome is an autoimmune thrombophilia: antibodies directed at phospholipid-binding proteins trigger clotting in arteries and veins throughout the body. It is th…
Myasthenia gravis is caused by antibodies that block acetylcholine receptors at the neuromuscular junction. The nerve fires normally, but the signal cannot be received by the musc…
Vitiligo is the selective destruction of melanocytes — the cells that produce skin pigment — by cytotoxic CD8+ T-cells that recognise melanocyte antigens as foreign. The resulting…
Ankylosing spondylitis targets the sacroiliac joints and spine with a unique perversity: instead of merely destroying joints, it replaces them with new bone. The final outcome, wi…
Sjögren's syndrome targets the exocrine glands — particularly the salivary and lacrimal glands — with lymphocytic infiltration that destroys the cells responsible for producing sa…
Celiac disease is the one autoimmune condition with a completely identified dietary trigger: gliadin, the alcohol-soluble fraction of wheat gluten. In genetically susceptible indi…
Psoriasis is driven by IL-17 and IL-23 cytokines that lock the skin into a state of hyperproliferation. Keratinocytes that normally renew over 28 days complete the cycle in 3–4 da…
Graves' disease is the mirror image of Hashimoto's: instead of destroying the thyroid, the immune system produces antibodies that mimic TSH and lock the gland into permanent stimu…
Hashimoto's thyroiditis is the most common cause of hypothyroidism in the developed world. Lymphocytes infiltrate the thyroid gland, destroying follicles and replacing functional …
Type 1 diabetes is not a failure of the pancreas — it is an immune attack on the pancreas. Autoreactive T-cells destroy the beta cells of the islets of Langerhans, eliminating the…
Ulcerative colitis confines its destruction to the inner lining of the large intestine, but the sustained mucosal inflammation produces continuous pain, bleeding, and over decades…
Crohn's disease is a transmural inflammation — it burns through the full thickness of the intestinal wall. Unlike ulcerative colitis which is limited to the surface, Crohn's can p…
Rheumatoid arthritis is driven by immune cells that invade the synovial lining of joints, forming an aggressive pannus tissue that erodes cartilage and bone. Unlike osteoarthritis…
In multiple sclerosis, autoreactive T-cells cross the blood-brain barrier and destroy myelin — the insulating sheath around nerve fibres. Without myelin, electrical signals slow, …
In lupus, the immune system produces antibodies against the body's own DNA. Those antibodies form immune complexes that lodge in the kidneys, skin, and joints — triggering inflamm…
Dr. Zsófia Clemens has shown that autoimmune disease begins not in the immune system — but in the gut. When the wrong foods damage your gut wall, foreign proteins flood your blood…