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The Gene: An Intimate History cover
★ Recommended
Genetics Reviewed May 2026

The Gene: An Intimate History

by Siddhartha Mukherjee

5 / 5

The story of the gene — from Mendel and Darwin to CRISPR — woven through the science, the history, and Mukherjees own family history of mental illness.

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The review

The Gene is what every introduction to genetics should be: rigorous, narrative, and morally serious. Mukherjee traces the concept of heredity from Mendels peas through Watson and Crick to the modern genome era — and asks what it means to edit the code of life now that we can.

The personal thread is what makes it land: Mukherjee uses his own family history of schizophrenia to ground abstract genetics in lived consequence. Read it before any conversation about polygenic scores, embryo selection, or germline editing.

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